Will that antidepressant work for you?

Will that antidepressant work for you? | July 26, 2020

The answer may be in your brain waves.

“Scientists have taken a small step toward personalizing treatment for depression.

A study of more than 300 people with major depression found that brain wave patterns predicted which ones were most likely to respond to the drug sertraline (Zoloft), a team reported in the journal Nature Biotechnology.

If the approach pans out, it could offer better care for the millions of people in the U.S. with major depression…”

For more information, go to https://www.npr.org/sections/health-shots/2020/02/10/804539572/will-that-antidepressant-work-for-you-the-answer-may-lie-in-your-brain-waves?utm_source=npr_newsletter&utm_medium=email&utm_content=20200211&utm_term=4394886&utm_campaign=news&utm_id=6400260&orgid=433

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Posted in Epilepsy, Medication Issues, News, Research
Tags: brain wave data, brain wave patterns, EEG equipment, major depression, multiple treatments, solution, Transcranial Magnetic Stimulation

11 Comments »

Many anti-depressants (like other drugs) are not tested on people over 65. Before you ingest, read carefully about the “side” effects. If you are over 65, ask your doctor or pharmacist what you can expect. It can be more than on the general population, or less. It can be way weird.

LikeLiked by 1 person

Comment by HoDo — July 26, 2020 @ 10:59 AM

Reply
I think that metabolism is the key. As you get older, your metabolism slows down and what may work for someone 40 years of age, may not work for those who are older. So, the strength of the efficiency of the med may need to be at a different level.

LikeLike

Comment by Phylis Feiner Johnson — July 26, 2020 @ 11:03 AM

Reply
At 41 & after my brain surgery, I was super excited knowing that I was out for over 10 hours & made it with no problems during brain surgery. After a week or so feeling like a NEW person, I was told & GIVEN PAXIL so that I would not be so excited or should I say ”looking forward to a no seizure life”. So I had to be on the ADD PAXIL. In 1 week I was ”depressed, had anxiety, felt on edge, had sleepless nights, & had STRESS more than not. I took myself off the drug after 2 weeks. When I went back & saw that chief neurologist & told him how i was feeling, he said to me,, YOU WENT OFF THE DRUG FOR THE REASONS YOU NEEDED TO BE ON THE DRUG. Then I said,,” I didn’t have those feelings until I went on YOUR drug PAXIL”. Then he ask how i was feeling then, & I said BETTER. So he tells me to go back on the drug & if I feel the same way, do as I did & go off the drug, Well DUHHHHHH,,, Why go back on it I asked is the same results happen ? Of course he had many brain terms to say WHAT & HOW taking any ADD can help brain chemistry, but for me NOTHING was further from the truth. I did as he said & in 1 week I went off the drug again & no more ADD’s since July 2001, my 1st & last time ever.

LikeLiked by 1 person

Comment by James D — July 26, 2020 @ 2:43 PM

Reply
- Paxil can be a curse, and is totally contraindicated for temporal lobe damage. It made me suicidal within a week. The doctor said, Take more. No, thank you.
  
  LikeLiked by 1 person
  
  Comment by HoDo — July 26, 2020 @ 3:09 PM
  
  Reply
- I hope you sent those docs packing.
  
  LikeLike
  
  Comment by Phylis Feiner Johnson — July 26, 2020 @ 3:55 PM
  
  Reply
- James,
  Congratulations for your achievements. Obviously, you should never have been on the drug in the first place as withdrawing from the drug proved more healthier than being on the drugs.
  Your case is one of the practical example for people to be extra cautious before taking all the drugs the Doctors prescribe.
  Gerrie
  
  LikeLiked by 1 person
  
  Comment by BahreNegash Eritrea — July 27, 2020 @ 1:28 AM
  
  Reply
Lexapro has helped me a lot by keeping my moods stable. 👍

LikeLiked by 1 person

Comment by lakefreak — July 27, 2020 @ 2:13 PM

Reply
After 1993, all drug trials in the US were by law supposed to include women and people of color. This has not been enforced. If you are over 65 or female or not “white,” you may not have been represented when the medication you’re taking was tested. See PMC5908758 at a number of web sites.

Sometimes drug trials are done overseas (sometimes without the informed consent of the participants). Sometimes the trials has been limited by those doing the testing. There are many ways of evading compliance.

If you are having problems with a medication, it might be worth the effort to try to learn on what populations it was tested.

LikeLiked by 1 person

Comment by HoDo — August 2, 2020 @ 4:57 PM

Reply
- Here’s an article that further illustrates your point, HoDo:
  
  Epilepsy Studies: True or False? https://epilepsytalk.wordpress.com/?p=11982&preview=true
  
  LikeLike
  
  Comment by Phylis Feiner Johnson — August 2, 2020 @ 7:49 PM
  
  Reply
  - Do you remember off the top of your head where you put things? Many thanks.
    
    LikeLike
    
    Comment by HoDo — August 3, 2020 @ 6:07 AM
  - I wish! 🙂
    
    LikeLike
    
    Comment by Phylis Feiner Johnson — August 3, 2020 @ 9:32 AM

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Many anti-depressants (like other drugs) are not tested on people over 65. Before you ingest, read carefully about the “side” effects. If you are over 65, ask your doctor or pharmacist what you can expect. It can be more than on the general population, or less. It can be way weird.

LikeLiked by 1 person

Comment by HoDo — July 26, 2020 @ 10:59 AM

I think that metabolism is the key. As you get older, your metabolism slows down and what may work for someone 40 years of age, may not work for those who are older. So, the strength of the efficiency of the med may need to be at a different level.

LikeLike

Comment by Phylis Feiner Johnson — July 26, 2020 @ 11:03 AM

At 41 & after my brain surgery, I was super excited knowing that I was out for over 10 hours & made it with no problems during brain surgery. After a week or so feeling like a NEW person, I was told & GIVEN PAXIL so that I would not be so excited or should I say ”looking forward to a no seizure life”. So I had to be on the ADD PAXIL. In 1 week I was ”depressed, had anxiety, felt on edge, had sleepless nights, & had STRESS more than not. I took myself off the drug after 2 weeks. When I went back & saw that chief neurologist & told him how i was feeling, he said to me,, YOU WENT OFF THE DRUG FOR THE REASONS YOU NEEDED TO BE ON THE DRUG. Then I said,,” I didn’t have those feelings until I went on YOUR drug PAXIL”. Then he ask how i was feeling then, & I said BETTER. So he tells me to go back on the drug & if I feel the same way, do as I did & go off the drug, Well DUHHHHHH,,, Why go back on it I asked is the same results happen ? Of course he had many brain terms to say WHAT & HOW taking any ADD can help brain chemistry, but for me NOTHING was further from the truth. I did as he said & in 1 week I went off the drug again & no more ADD’s since July 2001, my 1st & last time ever.

Comment by James D — July 26, 2020 @ 2:43 PM

Paxil can be a curse, and is totally contraindicated for temporal lobe damage. It made me suicidal within a week. The doctor said, Take more. No, thank you.

LikeLiked by 1 person

Comment by HoDo — July 26, 2020 @ 3:09 PM

I hope you sent those docs packing.

LikeLike

Comment by Phylis Feiner Johnson — July 26, 2020 @ 3:55 PM

James,
Congratulations for your achievements. Obviously, you should never have been on the drug in the first place as withdrawing from the drug proved more healthier than being on the drugs.
Your case is one of the practical example for people to be extra cautious before taking all the drugs the Doctors prescribe.
Gerrie

LikeLiked by 1 person

Comment by BahreNegash Eritrea — July 27, 2020 @ 1:28 AM

Lexapro has helped me a lot by keeping my moods stable. 👍

Comment by lakefreak — July 27, 2020 @ 2:13 PM

After 1993, all drug trials in the US were by law supposed to include women and people of color. This has not been enforced. If you are over 65 or female or not “white,” you may not have been represented when the medication you’re taking was tested. See PMC5908758 at a number of web sites.

Sometimes drug trials are done overseas (sometimes without the informed consent of the participants). Sometimes the trials has been limited by those doing the testing. There are many ways of evading compliance.

If you are having problems with a medication, it might be worth the effort to try to learn on what populations it was tested.

Comment by HoDo — August 2, 2020 @ 4:57 PM

Here’s an article that further illustrates your point, HoDo:

Epilepsy Studies: True or False? https://epilepsytalk.wordpress.com/?p=11982&preview=true

LikeLike

Comment by Phylis Feiner Johnson — August 2, 2020 @ 7:49 PM

- Do you remember off the top of your head where you put things? Many thanks.
  
  LikeLike
  
  Comment by HoDo — August 3, 2020 @ 6:07 AM
- I wish! 🙂
  
  LikeLike
  
  Comment by Phylis Feiner Johnson — August 3, 2020 @ 9:32 AM

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