Epilepsy Talk
For Refractory Epilepsy — Two AEDs and You’re Home Free!
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A recent University of Washington report, published in the journal of the American Academy of Neurology, found a combination of two common drugs, lamotrigine and valproate, is more effective in treating refractory epilepsy than other anti-epileptic regimens.
In a large-scale retrospective study of patients with very difficult-to-control epilepsy, researchers discovered that out of the 32 drug combinations studied, only the lamotrigine/valproate treatment regimen significantly decreased seizure frequency in this group. This specific combination reduced seizure frequency by about half, on average, compared to other regimens.
Tags: lamotrigine and valproate, more effective, reduce seizures by 50%, refractory epilepsy
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